Sheba Medical Center, ARC Innovation, and Paradigm Health Inc. Forge Strategic Partnership to Expand and Optimize Global Clinical Trials

Collaboration led by Sheba Medical Center’s research and innovation arms aim to scale an AI-driven clinical trial platform to revolutionize clinical trial processes

Sheba

 

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TEL AVIV, Israel, September 12, 2024Sheba Medical Center, Israel’s largest hospital and a global leader in clinical trials and medical innovation, and ARC Innovation, the innovation arm of Sheba, today announced a landmark partnership with Paradigm Health Inc. to establish a global network for clinical research. This strategic collaboration, formalized today during a signing ceremony at Sheba Medical Center as part of the ARC Summit 2024, positions Sheba, ARC, and Paradigm as the driving forces behind the clinical trial platform of the future. This collaboration will also expand the availability of, and patient access to, clinical trials that may be care options for patients with cancer and other serious diseases throughout Israel.

The partnership represents a shared vision between Sheba, ARC, and Paradigm to revolutionize clinical trial processes through an AI-driven platform. This platform is designed to optimize clinical trials by automating key processes, enhancing site selection, patient recruitment, engagement, and retention, and adapting to real-time data to refine trial protocols and site selections. By moving clinical trials from traditional stand-alone academic settings to patient-centered environments close to where patients live and receive their care, the platform to be scaled aims to improve inclusivity, reduce costs, and accelerate the development of new therapies, benefiting pharmaceutical companies, patients, researchers, and medical institutions alike. Patients will benefit from access to more options for advanced care closer to home, while reducing the burden of study operations on Sheba’s providers.

Integrating Paradigm’s state-of-the-art platform, Sheba and ARC will significantly increase trial capacity and enhance operational efficiency. Sheba’s Riva Koschitzky Oncology Clinical Research Unit is an international leader and preferred partner for global pharmaceutical companies conducting oncology trials, both early and late phase. Together, the organizations will create a streamlined operational model for clinical trials, supported by Paradigm’s platform and services, that will expand Sheba’s capacity to conduct clinical trials and help build a trials network at Sheba’s affiliated clinics across Israel. Patients will benefit from access to more options for advanced care closer to home, while reducing the burden of study operations on Sheba’s providers. The platform will streamline trial operations, including feasibility assessments, patient screening, recruitment, and data management, thereby reducing administrative burdens and costs.

In addition to enhancing Sheba’s clinical trial capabilities, ARC intends to expand the platform to its global ecosystem of hospitals utilizing Paradigm's platform. The clinical trial platform will standardize methodologies, improve access to innovative treatments, and accelerate medical research, reflecting both organizations' commitment to expanding and optimizing clinical research on a global scale.

This agreement is part of Sheba's commitment to becoming one of the world’s first fully-integrated AI based hospitals. Through ARC, Sheba is transforming healthcare by using data and AI solutions to enhance patient care, diagnostics, and treatment personalization. As a leader in developing and integrating AI in health care, Sheba collaborates with top institutions like the Mayo Clinic and others to integrate advanced AI solutions across its departments, positioning itself at the forefront of medical innovation.

Professor Eyal Zimlichman, MD, Chief Innovation and Transformation Officer at Sheba Medical Center and Founder and Director of ARC Innovation said: “Partnering with Paradigm allows us to leverage cutting-edge technologies to create a unified global network that standardizes and optimizes clinical trials, ensuring that life-saving treatments reach patients faster and more efficiently. Our co-development of the clinical trial platform of the future aligns with ARC’s mission to transform global health through innovation. With Paradigm’s cutting-edge platform, we can accelerate the pace of innovation and bring life-saving treatments to patients faster than ever before.”

Prof. Dror Harats, Head of Sheba Medical Center’s Research Authority said: “Partnering with Paradigm allows us to address the unsolved challenges of clinical trial operations in a systematic and coordinated manner. Sheba is a global leader in clinical trials and we’ve shown that technological advancement and clinical excellence go hand in hand. We are excited to leverage the Paradigm technology to help our clinical team provide each and every patient with the highest quality and most advanced treatment through clinical trials.”

Kent Thoelke, CEO of Paradigm: “Sheba Medical Center is a recognized world leader in clinical research, and we are honored to collaborate with ARC Innovation in this ambitious endeavor. By streamlining trial operations, we empower Sheba’s exceptional teams to focus on patient care and accelerate the development of new therapies. Together, we are building a global platform that will standardize and optimize clinical trials worldwide.”

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About ARC

ARC is powering the transformation of health. Through its continuous pipeline of innovation, ability to facilitate large-scale transformation, access to leading health organizations, and ability to drive economic growth and development, ARC equips all player-types in the ecosystem to transform global health. For more information, visit: https://arcinnovation.org

About Sheba Medical Center

The largest and most comprehensive medical center in the Middle East, Sheba Medical Center, Tel Hashomer is generating global impact through its medical care, research and healthcare transformation. Sheba’s City of Health boasts acute-care, rehabilitation, children’s, cancer and geriatric hospitals, research and innovation hubs, medical simulation center and center for disaster response on one comprehensive campus in the center of Israel. Sheba serves as a true hospital without borders, welcoming users and healthcare professionals from all over the world and consistently providing the highest-level medical care to all in need. Sheba has been ranked a World’s Best Hospital by Newsweek six years in a row (2019 – 2024). For more information, visit: https://sheba-global.com/

About Paradigm

Paradigm is rebuilding the clinical research ecosystem by creating a platform that enables equitable access to trials for all patients, while enhancing trial efficiency and reducing the barriers to participation for healthcare providers. Incubated by ARCH Venture Partners and backed by leading healthcare and life sciences investors, Paradigm aims to break down barriers across the trial ecosystem through one seamless infrastructure implemented at healthcare provider organizations, bringing potentially life-saving therapies to patients faster. For more information, visit: https://www.paradigm.inc/

For media inquiries please contact Raoul Wootliff at raoul@number10strategies.com or Jacquelyn Miller at jacquelyn.miller@paradigm.inc.